I'm hearing a big enough difference in the two pre's that I would not use the Mackie straight up. It's bigger than subtle, it's large. The Onyx has harsh highs, loud sloppy mids and underpowered bass. The Neve is tight from top to bottom and here's what the mackie doesn't have, depth and dimension, which you can only get through a well designed and manufactured circuit. The Onyx is also missing musicality and since that's what I do for hours on end, I wouldn't mix or record with it. After the tracks added up, so would the onyx's masked noise crerating a harsh, dry sounding, depthless mix, which I hate.