I went throught, Pro Tools, Cakewalk HS 2004, Acid Pro 3.0, and my computer was a headache. I finally bought a VS2480CD w/ 17" LCD and an RPC-1 Card for my PC. I think I died and went to heaven. I use Acid Pro 3.0 in the PC as a drum machine and send drum tracks to the VS to add the rest of the songs tracks to. I have Wave Lab so I can send my VS stereo Master tracks back to the PC for mastering or just master in the VS. I tried Sonar, it's OK but I like the hands on control I get with the VS. Sonar doesn't agree with my PC either so that's been a problem.
There are other systems out there that Tascam and Akia make, these systems are very stable and can link to your PC. I've had next to no problems with my VS2480CD and it never crashes on me. My PC, I'm on my 4th PC and many music programs and plugins but only one VS2480CD. If you have $5K to $7K to spend on a computer setup go with Pro Tools and a G5 Dual setup, I've heard a lot of good things about them. Something less expensive, Sonar, Cubase, Nuendo, they all are good for the money.
Do you like doing a lot of the computer editing, envelopes, etc? Then go that route. Myself, I'm an old 70s rocker and the hands on analog tape gear with knobs, pads, faders etc is what I relate to so the VS2480CD fits that bill, for me. The PC is still a headache and I'm still trying to make it work for me as good as the VS. I see you have a smaller VS unit so maybe that's a plus? At least you are familiar with it. Adding a 17" LCD to the VS is like adding Sonar or Pro Tools, you have the visual and that makes all the difference to me. Later, Frank.