Yes, even if there's audio in the gap. I have a consumer system at home of coarse, and the amp is clocked by the digi input from the DVD player. In the pregap, the clock stops, and then starts up again, but the amp has to reclock to the signal before it outputs. this can take 1-2 secs for this to happen. So not only do you loose the pregap but also a significant amount from the start of the song. I've always known this to be an issue with AC3 files on DVD's and having to have 2 secs preroll before audio so the amp can lock, but with CD's, it's seems to still be the case, unless i use the analog outputs.